Brain & Body Health Inc. is developing research and educational initiatives focused on cognitive health, whole-person approaches and the scientific evaluation of real-world outcomes. Specific research settings will be identified once appropriate study protocols and ethical review processes are in place.
Stage: Research planning and collaborator outreach
BBH is seeking qualified research collaborators to help design rigorous evaluations of cognitive-health programs. A prospective observational design may serve as a starting point, looking at changes over time in cognition, daily functioning, quality of life and caregiver experience.
Collaborators would help shape study design, outcome measures, participant protections and the interpretation of results. This work does not assume in advance that any program is effective.
Stage: Research development
BBH is developing a research focus on oral-systemic health and cognition, exploring potential relationships among oral health, the oral and gut microbiomes, systemic inflammation, metabolic and vascular health, and cognitive function. We are interested in responsible collaborations that can evaluate these relationships using appropriate methods, without assuming causality in advance.
This is an emerging area of research. It is not an established method for diagnosing or reversing Alzheimer's disease.
BBH is interested not only in whether oral and cognitive-health measures are associated, but also in the direction and context of those relationships. Some oral conditions may contribute to systemic inflammatory burden; other oral findings may reflect underlying metabolic, vascular, immune, medication-related, or behavioral factors. Research design must distinguish potential causes, mediators, consequences, and shared risk factors.
Stage: Content and collaboration development
BBH aims to translate research findings, limitations and emerging evidence into clear educational resources for families and professionals, including accurate explanations of what is known, what remains uncertain, and what requires further study. We welcome discussions with potential contributors who can help make this information accurate, accessible, and useful.
As projects take shape, we intend to explain each project’s purpose, stage, participating organizations, and the specific role of BBH. Research summaries will distinguish studies conducted elsewhere from findings produced through BBH’s own collaborations.
When results are available, our aim is to present the findings alongside their methods and limitations so readers can understand what the work does and does not establish.
Before any BBH study collects samples or health information from participants, it goes through these steps:
We define the research question, for example how oral health, gut health, inflammation and cognitive function may be related.
We write a study protocol that sets out who can take part, what will be collected and when, what will be measured, and how results will be analyzed.
We prepare an informed-consent process that explains what is collected and why, the possible risks, how privacy is protected, and that taking part is voluntary and can be stopped at any time.
The study is submitted to an Institutional Review Board (IRB), an independent ethics committee that reviews research involving people. The IRB may approve the study, ask for changes, or decide what level of review it needs.
Research-specific collection begins only after IRB approval or determination.
When a study takes place in a care setting, that setting’s qualified staff and laboratories handle clinical care and sample collection. BBH receives coded data, with a study number in place of a participant’s name, and focuses on study design, analysis, scientific collaboration and publication.
BBH’s International Scientific Advisory Committee advises on research priorities and methods. It does not replace an IRB.
Making support more accessible to families is part of BBH’s long-term charitable vision. Charitable support may help advance BBH’s research, education, scientific collaboration and future access initiatives. We will share details of formal giving or assistance programs once they are in place.
Brain & Body Health Inc. is a 501(c)(3) nonprofit advancing cognitive-health research, education, outcome evaluation and professional collaboration.
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